21 days in Cuba Itinerary

21 days in Cuba Itinerary

Created using Inspirock Cuba itinerary maker

Make it your trip
Fly
1
Havana
— 4 nights
Drive
2
Varadero
— 3 nights
Fly
3
Cayo Largo
— 3 nights
Bus
4
Cienfuegos
— 1 night
Drive
5
Trinidad
— 3 nights
Drive
6
Cayo Guillermo
— 2 nights
Drive
7
Camaguey
— 2 nights
Drive
8
Santiago de Cuba
— 2 nights
Fly

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Havana

— 4 nights

Rome of the Caribbean

Cuba's capital and major commercial center, Havana manages to be very old and very modern at the same time.
Havana is known for historic sites, nightlife, and museums. Your plan includes some of its best attractions: make a trip to Malecón of Havana, take a stroll through Christopher Columbus Cemetery (Cemetario de Colon), take in the local highlights with Walking tours, and steep yourself in history at El Morro.

To see reviews, ratings, photos, and other tourist information, you can read our Havana travel route builder site.

Amsterdam, The Netherlands to Havana is an approximately 13-hour flight. Due to the time zone difference, you'll gain 6 hours traveling from Amsterdam to Havana. Expect warmer weather when traveling from Amsterdam in September: highs in Havana hover around 36°C, while lows dip to 26°C. Wrap up your sightseeing on the 4th (Mon) to allow time to drive to Varadero.

Things to do in Havana

Historic Sites · Tours · Neighborhoods · Museums

Side Trip

Varadero

— 3 nights
One of the largest resort towns in the Caribbean, Varadero boasts a 20 km (12 mi) long stretch of sand, lined with hotels and all-inclusive resorts.
When in Varadero, make a side trip to see Pharmaceutical Museum in Matanzas, approximately Matanzas away. There's lots more to do: enjoy the sand and surf at Varadero Beach, meet the residents at Delfinario, hunt for treasures at Varadero Street Market, and get advice or help at Convention Center Plaza America.

To find more things to do, photos, maps, and tourist information, use the Varadero trip maker.

Drive from Havana to Varadero in 2 hours. Alternatively, you can take a shuttle; or do a combination of train and taxi. October in Varadero sees daily highs of 35°C and lows of 24°C at night. Wrap up your sightseeing on the 7th (Thu) to allow time to travel to Cayo Largo.

Things to do in Varadero

Outdoors · Parks · Beaches · Wildlife

Side Trip

Cayo Largo

— 3 nights
The stress of modern life feels a million miles away when you holiday on Cayo Largo, a small and unspoiled resort island off the coast of Cuba.
Change things up with these side-trips from Cayo Largo: Vinales (Jardin Botanico de Vinales, Valle de Vinales, &more). On the 9th (Sat), enjoy a perfect day by the water at Playa Paraiso. There's lots more to do: enjoy the sand and surf at Sirena Beach, stroll through Punta Mal Tiempo, and look for all kinds of wild species at Sea Turtle Hatchery.

To see other places to visit, maps, reviews, and more tourist information, you can read our Cayo Largo trip planner.

Traveling by flight from Varadero to Cayo Largo takes 3.5 hours. Alternatively, you can take a bus. In October in Cayo Largo, expect temperatures between 36°C during the day and 28°C at night. Finish your sightseeing early on the 10th (Sun) to allow enough time to take a bus to Cienfuegos.

Things to do in Cayo Largo

Parks · Beaches · Outdoors · Nature

Side Trip

Cienfuegos

— 1 night

Pearl of the South

The city of Cienfuegos sits in a scenic natural bay, attracting visitors from across the country and further afield since its establishment in the early 19th century.
On the 11th (Mon), admire the sheer force of El Nicho Waterfalls, get a taste of the local shopping with Galeria Santiago Hermes, then get a taste of the local shopping with Poco Bonito, then don't miss a visit to Parque Jose Marti, and finally ponder the world of politics at Museo de las Artes Palacio Ferrer.

To find traveler tips, ratings, maps, and more tourist information, use the Cienfuegos road trip planning site.

Traveling by bus from Cayo Largo to Cienfuegos takes 3.5 hours. October in Cienfuegos sees daily highs of 36°C and lows of 26°C at night. Wrap up your sightseeing on the 11th (Mon) to allow time to drive to Trinidad.

Things to do in Cienfuegos

Nature · Parks · Museums · Shopping

Trinidad

— 3 nights
Built on sugar and seemingly preserved in molasses, the town of Trinidad attracts visitors with its well-aged 19th century architecture and rustic charm, showcasing the sounds, scents, and sights of days gone by.
Trinidad is known for beaches, historic sites, and nightlife. Your plan includes some of its best attractions: enjoy the sand and surf at Ancon Beach, don't miss a visit to Plaza Mayor, take in the dramatic scenery at Salto del Caburni, and steep yourself in history at Valle de los Ingenios.

To see more things to do, where to stay, ratings, and more tourist information, read Trinidad trip itinerary planning site.

You can drive from Cienfuegos to Trinidad in 1.5 hours. Other options are to take a shuttle; or take a bus. Expect a daytime high around 36°C in October, and nighttime lows around 26°C. Finish up your sightseeing early on the 14th (Thu) so you can go by car to Cayo Guillermo.

Things to do in Trinidad

Parks · Wildlife · Nature · Outdoors

Side Trips

Cayo Guillermo

— 2 nights
A kay of the Jardines del Rey archipelago, Cayo Guillermo has become a popular international tourist destination, buoyed by the construction of luxury all inclusive resorts that dot the paradisal island.
On the 15th (Fri), relax and rejuvenate at Acuavida Spa Talaso and then discover the deep blue sea with Melia Cayo Coco Diving Center. Here are some ideas for day two: head off the coast to Cayo Media Luna, kick back and relax at Playa Pilar, and then kick back and relax at Cayo Guillermo.

To find other places to visit, traveler tips, where to stay, and tourist information, use the Cayo Guillermo day trip planning tool.

Traveling by car from Trinidad to Cayo Guillermo takes 4 hours. Alternatively, you can drive; or take a bus. October in Cayo Guillermo sees daily highs of 35°C and lows of 28°C at night. Finish your sightseeing early on the 16th (Sat) so you can drive to Camaguey.

Things to do in Cayo Guillermo

Outdoors · Parks · Beaches · Spas

Side Trip

Camaguey

— 2 nights
Camaguey encompasses the central section of Cuba and remains largely agricultural, its economy dependent on small-scale cattle raising and fruit production.
Kick off your visit on the 17th (Sun): relax in the rural setting at Rancho King Touristic Farm, get to know the fascinating history of Camaguey Centro, contemplate the long history of Casa Natal del Mayor (Ignacio Agramonte), then admire the architecture and history at Plaza del Carmen, and finally take in the exciting artwork at Martha Jimenez's Studio Workshop. Get ready for a full day of sightseeing on the next day: pause for some serene contemplation at Iglesia de Santa Ana, don't miss a visit to Plaza San Juan de Dios, pause for some serene contemplation at Iglecia de san juan de dios, make a trip to Gallery Larios, then appreciate the extensive heritage of Parque Ignacio Agramonte, and finally contemplate the long history of Iglesia Nuestra Señora De La Merced.

For ratings, more things to do, maps, and tourist information, read Camaguey itinerary website.

You can drive from Cayo Guillermo to Camaguey in 3.5 hours. Alternatively, you can do a combination of taxi and bus; or do a combination of taxi and train. Expect a daytime high around 36°C in October, and nighttime lows around 26°C. Wrap up your sightseeing on the 18th (Mon) to allow time to drive to Santiago de Cuba.

Things to do in Camaguey

Historic Sites · Museums · Parks · Shopping

Santiago de Cuba

— 2 nights
Santiago de Cuba has taken almost as much influence from Haiti and the Dominican Republic as it has from Havana, distilling a concoction of cultures to create a city with a distinct identity.
Kick off your visit on the 19th (Tue): take an in-depth tour of Casa de Diego Velazquez, see the interesting displays at Emilio Bacardi Moreau Museum, steep yourself in history at Moncada Barracks, then stroll the grounds of Cementerio Santa Ifigenia, then learn about all things military at Museo de la Lucha Clandestina, and finally explore the historical opulence of Castillo de San Pedro de la Roca.

To find more things to do, where to stay, and tourist information, you can read our Santiago de Cuba online vacation builder.

Traveling by car from Camaguey to Santiago de Cuba takes 5.5 hours. Alternatively, you can take a bus; or take a train. In October in Santiago de Cuba, expect temperatures between 36°C during the day and 27°C at night. Wrap up your sightseeing on the 20th (Wed) early enough to travel back home.

Things to do in Santiago de Cuba

Museums · Historic Sites

Cuba travel guide

4.4
Beaches · Historic Walking Areas · Landmarks
The largest island in the Caribbean, Cuba lies just 140 km (90 mi) south of Florida and captivates a growing number of Western visitors with its tropical landscapes and cultural attractions. Sightseeing in Cuba inevitably begins in Havana, a city of photogenic architecture, lively nightlife, and a passion for baseball. The country's smaller colonial towns usually feature central squares, ideal places to meet the locals under wrought-iron street lamps. Savvy visitors escape the cities during their Cuba holidays, devoting plenty of time to the country's charming countryside, where you can get the feel for this diverse land by conversing with friendly tobacco farmers and small-scale fruit producers.